Update on antifungal agents for paediatric patients
نویسندگان
چکیده
منابع مشابه
An update on the use of antifungal agents.
We summarize here data regarding the spectrum of action, the pharmacological aspects, the toxicological aspects and the clinical efficacy of liposomal amphotericin B, amphotericin B in colloidal dispersion, amphotericin B lipid complex, voriconazole and caspofungin. We discuss the use of these more recently introduced antifungal agents in terms of their safety, efficiency and cost. We also offe...
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Continued advancement of medical science offers life-saving treatment options for a variety of hematologic, oncologic, and rheumatologic conditions. Immunosuppression, a common therapeutic side-effect, predisposes patients to invasive fungal infections, which are escalating in prevalence. The development of effective, welltolerated antifungals has lagged behind the advances of antibacterial the...
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Animal studies did not control for physiological variables like blood pressure, oxygenation, acidosis, hypoglycemia; factors that can induce apoptosis in these anaesthetized animals. Also drug doses and duration of exposure in animal studies cannot be transferred to humans. Apoptosis secondary to anaesthetic exposure is only seen at certain stages of brain development and is not uniform. It is ...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2010
ISSN: 1198-743X
DOI: 10.1111/j.1469-0691.2010.03334.x